 | Blood, Guts and Sunshine: The History of Horror Made in Florida (2021) as Self [archival] |
 | Herschell Gordon Lewis: The Godfather of Gore (2019) as Self |
 | Killer Campout (2017) as Himself- Voice |
 | BloodMania (2017) as The Host |
 | How Herschell Found His Niche (2016) as himself |
 | Blood Feast (2016) as Professor Lou Herschell |
 | They Came from the Swamp: The Films of William Grefé (2016) as Himself |
 | B-Documentary (2015) as Himself |
 | Terror Toons 3 (2015) as Himself |
 | That's Sexploitation! (2013) as Self (archive footage) |
 | Tonight You Die (2011) |
 | Produce Your Own Damn Movie! (2011) as Self |
 | American Grindhouse (2011) as Himself |
 | Under the Scares (2010) as Self |
 | Herschell Gordon Lewis: The Godfather of Gore (2010) |
 | The Uh-oh Show (2009) as Uncle Herschell (uncredited) |
 | 7 Deadly Sins: Inside The Ecomm Cult (2009) |
 | Smash Cut (2009) as Fred Sandy / Radio Announcer |
 | Psycho Holocaust (2009) as Radio News Broadcaster (voice) |
 | Book of Lore (2007) as Bingo Record (voice) |
 | Horror Business (2005) as Himself |
 | Chainsaw Sally (2004) as Mr. Gordon |
 | Bits and Pieces: Bringing Death to Life (2003) as Self |
 | Divine Trash (2000) as Self |
| | An Evening with H.G. Lewis (1989) as Self |
 | Crystalstone (1987) as Antique Dealer |
 | How to Make a Doll (1968) as Narrator (voice) (uncredited) |
 | The Alley Tramp (1968) as Radio Reporter Gene Stallion (voice) |
 | The Gruesome Twosome (1967) as Radio Announcer (voice) (uncredited) |
 | A Taste of Blood (1967) as The Limey Seaman / Baron Khron (voice) (as Seymour Sheldon) |
 | Something Weird (1967) as Narrator (voice) (as Sheldon Seymour) |
 | Jimmy, the Boy Wonder (1966) as Narrator (voice) (uncredited) |
 | Scum of the Earth (1963) as Narrator (voice) |
 | Goldilocks and the Three Bares (1963) as Voice Introducing Sonny Seymour (voice) |
 | Blood Feast (1963) as Radio Announcer (voice) (uncredited) |
 | Living Venus (1961) as Man on Street (uncredited) |
