 | Donkey (2028) as Donkey (voice) |
 | Shrek 5 (2027) as Donkey (voice) |
 | Michael Jackson: A Life in Music (2026) as Self (archive footage) |
 | The 51st AFI Life Achievement Award: A Tribute to Eddie Murphy (2026) as Self |
 | Being Eddie (2025) as Self |
 | John Candy: I Like Me (2025) as Self - Actor, Saturday Night Live (archive footage) |
 | The Pickup (2025) as Russell |
 | Ladies & Gentlemen... 50 Years of SNL Music (2025) as Self - SNL Cast Member 1980-1984 |
 | Beverly Hills Cop: Axel F (2024) as Axel Foley |
 | Outstanding: A Comedy Revolution (2024) as Self (archive footage) (uncredited) |
 | Candy Cane Lane (2023) as Chris Carver |
 | Eddie Murphy, le roi noir d'Hollywood (2023) as Kendisi (arşiv görüntüleri) |
 | You People (2023) as Akbar |
 | Eddie Murphy: Laugh 'Til it Hurts (2021) as Self |
 | Coming 2 America (2021) as Prince Akeem / Clarence / Saul / Randy Watson |
 | Feeding America Comedy Festival (2020) as Self |
 | Dolemite Is My Name (2019) as Rudy Ray Moore |
 | Won't You Be My Neighbor? (2018) as Self - Mr. Robinson (archive footage) |
 | Mr. Church (2016) as Henry Church |
 | Eat Drink Laugh: The Story of The Comic Strip (2014) as Self |
 | Shrek Stories (2013) as Donkey (voice) |
 | Whoopi Goldberg Presents Moms Mabley (2013) as Self |
 | Eddie Murphy: One Night Only (2012) as Self |
 | Dreamworks: Holiday Classics (2012) as Donkey (voice) |
 | Shrek's Thrilling Tales (2012) as Donkey (voice) |
 | Yo! The Story of ‘Yo! MTV Raps’ (2012) as Self |
 | A Thousand Words (2012) as Jack McCall |
 | Shrek: Once Upon a Time (2011) as Self |
 | Method to the Madness of Jerry Lewis (2011) as Self |
 | Tower Heist (2011) as Slide |
 | Donkey's Christmas Shrektacular (2010) as Donkey (voice) |
 | Shrek's Yule Log (2010) as Donkey (voice) |
 | The Women of SNL (2010) as Gumby (archive footage) |
 | Shrek Forever After (2010) as Donkey (voice) |
 | Imagine That (2009) as Evan Danielson |
 | Hollywood Singing and Dancing: A Musical History (2008) as Self |
 | Meet Dave (2008) as Dave / Captain |
 | Shrek the Halls (2007) as Donkey (voice) |
 | Shrek the Third (2007) as Donkey (voice) |
 | Norbit (2007) as Norbit / Rasputia / Mr. Wong |
 | Dreamgirls (2006) as James 'Thunder' Early |
 | Fuck (2006) as Self (archive footage) (uncredited) |
 | Saturday Night Live in the '80s: Lost and Found (2005) as Self |
 | Far Far Away Idol (2004) as Donkey (voice) |
 | Shrek 2 (2004) as Donkey (voice) |
 | Shrek 3-D (2004) as Donkey (voice) |
 | The Haunted Mansion (2003) as Jim Evers |
 | 101 Most Shocking Moments in Entertainment (2003) as Self (archive footage) |
 | Daddy Day Care (2003) as Charlie Hinton |
 | I Spy (2002) as Kelly Robinson |
 | The Ultimate Collection starring Johnny Carson - The Best of the 70s and 80s (2002) as Self (archive footage) |
 | The Adventures of Pluto Nash (2002) as Pluto Nash |
 | Showtime (2002) as Officer Trey Sellars |
 | Shrek in the Swamp Karaoke Dance Party (2001) as Donkey (voice) (singing voice) |
 | Dr. Dolittle 2 (2001) as Dr. John Dolittle |
 | Shrek (2001) as Donkey (voice) |
 | Creating a Fairy Tale World: The Making of Shrek (2001) as Self |
 | Nutty Professor II: The Klumps (2000) as Sherman Klump / Buddy Love / Granny Klump / Mama Klump / Papa Klump / Young Papa Klump / Ernie Klump / Lance Perkins |
 | Saturday Night Live: Christmas (1999) as Self |
 | Bowfinger (1999) as Kit Ramsey / Jeffernson 'Jiff' Ramsey |
 | Life (1999) as Rayford Gibson |
 | Holy Man (1998) as G |
 | Doctor Dolittle (1998) as Dr. John Dolittle |
 | Mulan (1998) as Mushu (voice) |
 | Saturday Night Live: The Best of Eddie Murphy (1998) as Self (archive footage) |
 | Metro (1997) as Inspector Scott Roper |
 | The Nutty Professor (1996) as Sherman Klump / Buddy Love / Lance Perkins / Papa Klump / Mama Klump / Grandma Klump / Ernie Klump |
 | The Garth Brooks Video Collection, Vol. 2 (1996) as Self (We Shall Be Free Music Video) |
 | Vampire in Brooklyn (1995) as Maximillian / Pauly / Guido |
 | Beverly Hills Cop III (1994) as Axel Foley |
 | But... Seriously (1994) as Self (archive footage) |
 | Michael Jackson: Dangerous - The Short Films (1993) as King (uncredited) |
 | The Distinguished Gentleman (1992) as Thomas Jefferson Johnson |
 | Boomerang (1992) as Marcus Graham |
 | Michael Jackson: Remember The Time (1992) as King (uncredited) |
 | Another 48 Hrs. (1990) as Reggie Hammond |
 | Tongues Untied (1990) as Self (archive footage) |
 | Common Threads: Stories from the Quilt (1989) as Self (archive footage) |
 | Harlem Nights (1989) as Quick |
 | Saturday Night Live: 15th Anniversary (1989) as Self (archive footage) |
 | The Best of Eddie Murphy: Saturday Night Live (1989) as Self (archive footage) |
 | Coming to America (1988) as Prince Akeem / Clarence / Randy Watson / Saul |
 | Eddie Murphy Raw (1987) as Self |
 | Beverly Hills Cop II (1987) as Axel Foley |
 | Uptown Comedy Express (1987) |
 | The Golden Child (1986) as Chandler Jarrell |
 | Mike Tyson vs Trevor Berbick (1986) as Self |
 | The Joe Piscopo New Jersey Special (1986) as Self |
 | B.B. King: Into the Night (1985) as Self |
 | Beverly Hills Cop (1984) as Axel Foley |
 | The Joe Piscopo Special (1984) as Self / Carl Lewis |
 | Best Defense (1984) as Landry |
 | Eddie Murphy: Delirious (1983) as Self |
 | Trading Places (1983) as Billy Ray Valentine |
 | 48 Hrs. (1982) as Reggie Hammond |
| | Untitled Grumpy Old Men Remake |
| | Attachment Parenting |
| | Blue Falcon |
| | The Pink Panther as Inspector Clouseau |
