 | Coastal (2025) as Self |
 | Buckle Up (2023) as Angel |
 | American Badass: A Michael Madsen Retrospective (2022) as Self |
 | Mickey Rourke : L'homme blessé (2022) |
 | Undateable John (2019) as Rose |
 | The Sound of a Wild Snail Eating (2019) as Narrator (voice) |
 | Papa (2018) as Sarah Freidman |
 | The Slider (2017) as Carol |
 | Sicilian Vampire (2015) as Carmelina Trafficante |
 | Awaken (2015) as Mao |
 | Father Rupert Mayer (2015) as Joanna Sebastian |
 | A Hitman in London (2015) as Zhanna |
 | I Am Michael (2015) as Deborah |
 | 2047 - Sights of Death (2014) as Major Anderson |
 | American Mustang (2013) as The Advocate |
 | Zombie Night (2013) as Birdie |
 | Arise (2013) as Narrator |
 | Social Nightmare (2013) as Susan Hardy |
 | The Hot Flashes (2013) as Ginger Peabody |
 | Pussy Riot: The Movement (2013) as Narrator |
 | Garbage (2013) as Daryl |
 | The Carbon Rush (2012) as Narrator |
 | A Closed Book (2012) as Jane Ryder |
 | Eldorado (2012) as The Stranger |
 | Your American Teen (2012) as Self |
 | Lovemakers (2011) as Mimi |
 | Celebrity Nude Revue: Easy 80's Volume 1 (2011) as Self (archive footage) |
 | Save the Farm (2011) |
 | Kill Bill: The Whole Bloody Affair (2011) as Elle Driver (California Mountain Snake) |
| | Pipe Dreams (2011) as Narrator |
| | So Right So Smart (2009) as Narrator |
 | Waking Sleeping Beauty (2009) as Madison (archive footage) |
| | Starz Inside - Unforgettably Evil (2009) as Self |
 | Amazing Racer (2009) as Rita Baker |
 | Storm Seekers (2009) as Leah Kaplan |
 | The Garden (2008) as Self |
 | Kung Fu Killer (2008) as Jane |
 | Dark Honeymoon (2008) as Jan |
 | The Devil's Ground (2008) as Carrie Mitchel |
 | Vice (2008) as Salt |
 | Shark Swarm (2008) as Brook Wilder |
 | IMAX Dolphins and Whales: Tribes of the Ocean (2008) as Narrator (voice) |
 | Dangerous Days: Making Blade Runner (2007) as Self |
| | Fashion Forward: Wardrobe and Styling (2007) as Self |
 | Cosmic Radio (2007) as Daryl Hannah |
 | All the Good Ones Are Married (2007) as Alex |
 | Being Michael Madsen (2007) as Self |
 | The Poet (2007) as Marlene Konig |
 | Olé (2006) as Maggie Granger |
 | Keeping Up with the Steins (2006) as Sandy / Sacred |
 | Final Days of Planet Earth (2006) as Liz Quinlan |
 | Careful What You Wish For (2004) as Store Patron |
 | Stories of Lost Souls (2004) as Herself |
 | Silver City (2004) as Maddy Pilager |
 | The Making of 'Kill Bill Vol. 2' (2004) as Self |
 | Kill Bill: Vol. 2 (2004) as Elle Driver 'California Mountain Snake' |
 | Yo puta (2004) as Adriana |
 | Making a 'Splash' (2004) as Self - 'Madison' |
| | Bare Knuckle Filming: The Construction of Northfork (2003) |
 | Kill Bill: Vol. 1 (2003) as Elle Driver |
 | Casa de los Babys (2003) as Skipper |
 | Northfork (2003) as Flower Hercules |
 | The Job (2003) as CJ March |
 | The Big Empty (2003) as Stella |
| | Supermarket (2003) as Self |
| | Strip Notes (2002) |
 | Cowboy Up (2002) as Celia Jones |
 | Searching for Debra Winger (2002) as Self |
 | AFI's 100 Years... 100 Passions: America's Greatest Love Stories (2002) as Self |
 | Hard Cash (2002) as Virginia |
 | A Walk to Remember (2002) as Cynthia Carter |
 | Dancing at the Blue Iguana (2001) as Angel |
 | Jackpot (2001) as Bobbi |
 | First Target (2000) as Alex McGregor |
 | Wildflowers (2000) as Sabine |
 | On the Edge of 'Blade Runner' (2000) as Self |
 | Hide and Seek (2000) as Anne White |
 | Diplomatic Siege (1999) as Erica Long |
 | Zapatista (1999) as Narrator (voice) |
 | My Favorite Martian (1999) as Lizzie |
 | Speedway Junky (1999) as Veronica |
 | Addams Family Reunion (1998) as Morticia Addams |
 | Hi-Life (1998) as Maggie |
 | Rear Window (1998) as Claudia Henderson |
 | The Real Blonde (1998) as Kelly |
 | The Gingerbread Man (1998) as Lois Harlan |
 | Rescuers: Stories of Courage - Two Families (1998) as Maria Althoff |
 | Bobcat Goldthwait Comedy Central "Pulp Comics" (1996) as Mona |
 | The Last Days of Frankie the Fly (1996) as Margaret |
 | The Good, The Bad, and the Beautiful (1996) as Self |
 | Grumpier Old Men (1995) as Melanie Gustafson |
 | Two Much (1995) as Liz |
 | The Tie That Binds (1995) as Leann Netherwood |
 | Les Cent et Une Nuits de Simon Cinéma (1995) as Mute Actress in Hollywood (uncredited) |
 | Attack of the 50 Ft. Woman (1994) as Nancy Archer |
 | The Little Rascals (1994) as Miss Crabtree |
 | Grumpy Old Men (1993) as Melanie |
 | Memoirs of an Invisible Man (1992) as Alice Monroe |
 | At Play in the Fields of the Lord (1991) as Andy Huben |
 | The Best of Disney: 50 Years of Magic (1991) as Self |
 | Crazy People (1990) as Kathy Burgess |
 | Steel Magnolias (1989) as Annelle Dupuy |
 | Crimes and Misdemeanors (1989) as Lisa Crosley |
 | High Spirits (1988) as Mary Plunkett |
 | Nelson Mandela 70th Birthday Tribute (1988) as Self |
 | Wall Street (1987) as Darien Taylor |
 | Roxanne (1987) as Roxanne Kowalski |
 | Legal Eagles (1986) as Chelsea Deardon |
 | The Clan of the Cave Bear (1986) as Ayla |
 | The Pope of Greenwich Village (1984) as Diane |
 | Splash (1984) as Madison |
 | Reckless (1984) as Tracey Prescott |
 | The Final Terror (1983) as Windy |
 | Summer Lovers (1982) as Cathy Featherstone |
 | Blade Runner (1982) as Pris |
 | Paper Dolls (1982) as Taryn Blake |
 | Hard Country (1981) as Loretta |
 | The Fury (1978) as Pam |
 | Naya: Legend of the Golden Dolphin |
| | Coastal Director |
| | Coastal Cinematography |
 | Barn Director |
| | Barn Additional Director of Photography |
 | The Times Director |
 | Fireside Session II Cinematography |
| | Fireside Session II Director |
 | Fireside Session I Director |
| | Fireside Session I Cinematography |
 | Mountaintop Producer |
| | Mountaintop Director |
 | Paradox Director |
| | Paradox Writer |
 | Neil Young: Hometown Director |
| | Neil Young: Hometown Art Direction |
 | The Monsanto Years Director |
| | The Monsanto Years Camera Operator |
 | Greedy Lying Bastards Executive Producer |
| | Vice Executive Producer |
| | Strip Notes Director |
| | Wildflowers Executive Producer |
| | Attack of the 50 Ft. Woman Co-Producer |
 | Warrior: The Life of Leonard Peltier Thanks |
