| Henry David Thoreau (2026) as Henry David Thoreau (voice) |
| Making Wicked: For Good (2025) as Self |
| Wicked: For Good (2025) as The Wonderful Wizard of Oz |
| Wicked: For Good - A Sneak Peek (2025) as Self |
| Wicked: One Wonderful Night (2025) as Self |
| Meister der Apokalypse - Roland Emmerich (2025) as Self |
| Making Wicked (2024) as Self |
| Henry Mancini: 100 at the Hollywood Bowl (2024) as Self / Host |
| Defying Gravity: The Curtain Rises on Wicked (2024) as Self |
| Wicked (2024) as The Wonderful Wizard of Oz |
| They Shot the Piano Player (2023) as Jeff Harris (voice) |
| Asteroid City (2023) as The Alien |
| Jurassic Greatest Moments: Jurassic Park to Jurassic World (2022) as Self |
| Jurassic World Dominion (2022) as Ian Malcolm |
| Fiddler's Journey to the Big Screen (2022) as Narrator |
| Beauty and the Beast: A Comic Relief Pantomime for Christmas (2021) as A Table |
| The Boss Baby: Family Business (2021) as Dr. Armstrong (voice) |
| Time Warp Vol. 2: Horror and Sci-Fi (2020) as Self |
| Time Warp Vol. 1: Midnight Madness (2020) as Self |
| #NoJoke (2019) as Self |
| The Mountain (2019) as Dr. Wallace Fiennes |
| Peanuts in Space: Secrets of Apollo 10 (2019) as Self |
| Jenny Lewis' On The Line Online (2019) as Self |
| A Place We Call Reality (2018) as Self (uncredited) |
| Fallen Kingdom: The Conversation (2018) as Self |
| Fallen Kingdom: Malcolm's Return (2018) as Self |
| Hotel Artemis (2018) as Orian "Wolf King" Franklin / Niagara |
| Jurassic World: Fallen Kingdom (2018) as Ian Malcolm |
| Always at The Carlyle (2018) as Self |
| Seth Rogen's Hilarity for Charity (2018) as Self |
| Isle of Dogs (2018) as Duke (voice) |
| Team Darryl (2018) as En Dwi Gast / Grandmaster |
| Spielberg (2017) as Self |
| Thor: Ragnarok (2017) as Grandmaster |
| Tour de Pharmacy (2017) as Marty Hass Present Day |
| The Fabulous Allan Carr (2017) as Self (archive) |
| Guardians of the Galaxy Vol. 2 (2017) as En Dwi Gast / Grandmaster (uncredited) |
| Miyubi (2017) as The Creator |
| Stephen Colbert's Live Election Night Democracy's Series Finale (2016) as Self |
| The War of 1996: A United World News Special (2016) as David Levinson |
| Independence Day: Resurgence (2016) as David Levinson |
| Another Day: The Making of 'Independence Day: Resurgence' (2016) as Self |
| Resurgence: It's Early Albuquerque (2016) as David Levinson |
| Unity (2015) as Narrator (voice) |
| Mortdecai (2015) as Milton Krampf |
| The Grand Budapest Hotel (2014) as Deputy Kovacs |
| Le Week-End (2013) as Morgan |
| Zambezia (2012) as Ajax (voice) |
| Tim and Eric's Billion Dollar Movie (2012) as Chef Goldblum |
| Return to Jurassic Park (2011) as Self |
| Morning Glory (2010) as Jerry Barnes |
| The Switch (2010) as Leonard |
| Adam Resurrected (2008) as Adam Stein |
| The Making of 'Fay Grim' or: How Do You Spell Espionage? (2007) as Himself |
| Fay Grim (2007) as Agent Fulbright |
| Man of the Year (2006) as Stewart |
| Pittsburgh (2006) as Self |
| Mini's First Time (2006) as Mike Rudell |
| Fear of the Flesh: The Making of The Fly (2005) as Self |
| This Is an Adventure (2005) as Self |
| Matthew Gray Gubler's Life Aquatic Intern Journal (2005) as Self |
| Dallas 362 (2005) as Bob |
| On the Set: 'The Life Aquatic with Steve Zissou' (2005) as Self / Alistair |
| Incident at Loch Ness (2004) as Self - Party Guest |
| The Life Aquatic with Steve Zissou (2004) as Alistair Hennessey |
| Stories of Lost Souls (2004) as Himself |
| Hollywood's Creepiest Creatures (2004) as Self |
| 100 Greatest Sexy Moments (2003) as Self |
| Abby Singer (2003) as Jeff Goldblum (uncredited) |
| Spinning Boris (2003) as George Gorton |
| Realizing The Right Stuff (2003) as Self |
| Supermarket (2003) as Self |
| War Stories (2003) as Ben Dansmore |
| Robbie the Reindeer: Legend of the Lost Tribe (2002) as White Rabbit (voice) |
| Saturday Night Live: The Best of Will Ferrell (2002) as Dr. Ken Waller (archive footage) |
| Igby Goes Down (2002) as D.H. |
| One of the Hollywood Ten (2002) as Herbert Biberman |
| Run Ronnie Run (2002) as Self |
| Buckaroo Banzai Declassified (2002) as Self |
| Festival in Cannes (2001) as Self (uncredited) |
| Cats & Dogs (2001) as Professor Brody |
| Playboy Mansion Parties Uncensored (2001) as Self |
| Perfume (2001) as Jamie |
| Chain of Fools (2001) as Avnet |
| Welcome to Hollywood (2000) as Jeff Goldblum |
| Auggie Rose (2000) as John Nolan |
| Altman on His Own Terms (2000) as Narrator / Self |
| Playboy: Playmate Pajama Party (1999) |
| The Prince of Egypt: From Dream to Screen (1999) as Self (archive footage) |
| From Star Wars to Star Wars: The Story of Industrial Light & Magic (1999) as Self |
| The Big Chill: A Reunion (1999) as Self |
| The Prince of Egypt (1998) as Aaron (voice) |
| Holy Man (1998) as Ricky Hayman |
| Roswell Top Secret (1998) as Self |
| Hollywood Dreamers (1997) as Self |
| The Story of Bean (1997) as Self |
| The Lost World: Jurassic Park (1997) as Ian Malcolm |
| The Making of 'The Lost World' (1997) as Self |
| Mad Dog Time (1996) as Mickey Holliday |
| Independence Day: The ID4 Invasion (1996) as Self |
| The Making of 'Independence Day' (1996) as Self - Host |
| Independence Day (1996) as David Levinson |
| The Great White Hype (1996) as Mitchell Kane |
| Powder (1995) as Donald Ripley |
| Nine Months (1995) as Sean Fletcher |
| The Making of 'Jurassic Park' (1995) as Self / Ian Malcolm |
| Hideaway (1995) as Hatch Harrison |
| The Real Jurassic Park (1993) as Narrator |
| Sesame Street Jam: A Musical Celebration (1993) as Self (segment "Monster in the Mirror") |
| Lush Life (1993) as Al gorky |
| Jurassic Park (1993) as Malcolm |
| Shooting Elizabeth (1992) as Howard Pigeon |
| Fathers & Sons (1992) as Max |
| The Player (1992) as Jeff Goldblum |
| Deep Cover (1992) as David Jason |
| Robert Altman's Players (1992) as Self |
| The Favour, the Watch and the Very Big Fish (1991) as Pianist |
| Framed (1990) as Wiley |
| Sing! Sesame Street Remembers Joe Raposo and His Music (1990) as Self |
| Mister Frost (1990) as Mr. Frost |
| El sueƱo del mono loco (1989) as Daniel Gillis |
| The Fly II (1989) as Seth Brundle (archive footage) (uncredited) |
| The Tall Guy (1989) as Dexter King |
| Earth Girls Are Easy (1988) as Mac |
| Vibes (1988) as Nick Deezy |
| Life Story (1987) as Jim Watson |
| Beyond Therapy (1987) as Bruce |
| Long Live the New Flesh: The Films of David Cronenberg (1987) as Self (archive footage) |
| The Fly (1986) as Seth Brundle |
| The Town Where No One Got Off (1986) as Cogswell |
| Looney Tunes 50th Anniversary (1986) as Self |
| Transylvania 6-5000 (1985) as Jack Harrison |
| Silverado (1985) as Slick |
| Into the Night (1985) as Ed Okin |
| B.B. King: Into the Night (1985) as Self |
| The Adventures of Buckaroo Banzai Across the 8th Dimension (1984) as New Jersey |
| Ernie Kovacs: Between the Laughter (1984) as Ernie Kovacs |
| The Right Stuff (1983) as NASA Recruiter |
| The Big Chill (1983) as Michael Gold |
| Rehearsal for Murder (1982) as Leo Gibbs |
| Threshold (1981) as Dr. Aldo Gehring |
| The Legend of Sleepy Hollow (1980) as Ichabod Crane |
| Invasion of the Body Snatchers (1978) as Jack Bellicec |
| Thank God It's Friday (1978) as Toni Di Marco |
| Remember My Name (1978) as Mr. Lee Nudd |
| Between the Lines (1977) as Max |
| Annie Hall (1977) as Lacey Party Guest |
| The Sentinel (1977) as Jack |
| Special Delivery (1976) as Snake |
| St. Ives (1976) as Hood |
| Next Stop, Greenwich Village (1976) as Clyde Baxter |
| Nashville (1975) as Tricycle Man |
| California Split (1974) as Lloyd Harris |
| Death Wish (1974) as Freak #1 |
| The Liar as Donald Trefusis |
| The Price of Admission as Alexander Taft |
| Broadway: The Next Generation as Self |