 | Dernsie: The Amazing Life of Bruce Dern (2026) |
 | Is This Thing On? (2025) as Tess Novak |
 | The Making of Jay Kelly (2025) as Self - Liz |
 | Jay Kelly (2025) as Liz |
 | Caught Stealing (2025) as Hank's Mom (uncredited) |
 | David Lynch, une énigme à Hollywood (2025) as Self - Actor |
 | Carole & Grey (2024) as Laura Dern |
 | Lonely Planet (2024) as Katherine Loewe |
 | OZI: Voice of the Forest (2024) as Seema |
 | 2023 Rock & Roll Hall of Fame Induction Ceremony (2023) as Self |
 | Common Ground (2023) as Self |
 | The Endangered Generation? (2023) as Self (voice) |
 | Carol Burnett: 90 Years of Laughter + Love (2023) as Self - Guest |
 | The Son (2022) as Kate |
 | Joyce Carol Oates: A Body in the Service of Mind (2022) as Voice |
 | Halftime (2022) as Self |
 | Jurassic Greatest Moments: Jurassic Park to Jurassic World (2022) as Self |
 | Jurassic World Dominion (2022) as Ellie Sattler |
 | Sheryl (2022) as Self |
 | A Night at the Academy Museum (2021) as Self |
 | The Making of "Marriage Story" (2020) as Self |
 | Crazy, Not Insane (2020) as Literary Voice of Dorothy Lewis (voice) |
 | Grizzly II: Revenge (2020) as Tina |
 | Little Women (2019) as Marmee March |
 | Marriage Story (2019) as Nora Fanshaw |
 | Marriage Story: From the Pages to the Performances (2019) as Self |
 | Trial by Fire (2019) as Elizabeth Gilbert |
 | J.T. LeRoy (2019) as Laura Albert |
 | Cold Pursuit (2019) as Grace Coxman |
 | The Director and the Jedi (2018) as Self |
 | The Force of Sound (2018) as Vice-Admiral Holdo (archive footage) |
 | The Tale (2018) as Jennifer |
 | Downsizing (2017) as Laura Lonowski |
 | Star Wars: The Last Jedi (2017) as Vice Admiral Holdo |
 | The Man with the Gray Elevated Hair (2017) as Self |
 | A Bloody Finger in Your Mouth (2017) as Self |
 | The Number of Completion (2017) as Self |
 | Spielberg (2017) as Self |
 | Bobbi Jene (2017) as Self |
 | The Good Time Girls (2017) as Clementine |
 | The Words That Built America (2017) as Self - Reader: Declaration of Independence |
 | The Black Ghiandola (2017) as Doctor |
 | Wilson (2017) as Pippi |
 | The Founder (2016) as Ethel Kroc |
 | Blue Velvet Revisited (2016) as Self |
 | Certain Women (2016) as Laura |
 | 99 Homes (2015) as Lynn Nash |
 | Bravetown (2015) as Annie |
 | Wild (2014) as Bobbi Grey |
 | When the Game Stands Tall (2014) as Bev Ladouceur |
 | The Fault in Our Stars (2014) as Frannie Lancaster |
 | 9 Kisses (2014) as Woman on Bench |
 | Trespassing Bergman (2013) as Self |
 | The Master (2012) as Helen Sullivan |
 | Final Cut: Hölgyeim és uraim (2012) as (archive footage) |
 | Blue Velvet: The Lost Footage (2011) as Sandy Williams |
 | Everything Must Go (2011) as Delilah |
 | Fight for Your Right Revisited (2011) as Cafe Patron |
 | Return to Jurassic Park (2011) as Self |
 | The Hill Chris Climbed: The Gridiron Heroes Story (2011) as Self |
 | Little Fockers (2010) as Prudence |
 | Tenderness (2009) as Teresa |
 | The Monday Before Thanksgiving (2008) as Theresa |
 | Recount (2008) as Katherine Harris |
 | Lynch (one) (2007) as Self |
 | Lynch 2 (2007) as Self |
 | More Things That Happened (2007) as Susan Blue |
 | Year of the Dog (2007) as Bret |
 | Inland Empire (2006) as Nikki Grace / Susan Blue |
 | Lonely Hearts (2006) as Rene Fodie |
 | The Prize Winner of Defiance, Ohio (2005) as Dortha Schaefer |
 | Happy Endings (2005) as Pam |
 | Love, Death, Elvis & Oz: The Making of Wild at Heart (2004) |
 | We Don't Live Here Anymore (2004) as Terry Linden |
 | Widespread Panic: Panic In the Streets (2002) as Self |
 | Searching for Debra Winger (2002) as Self |
 | Damaged Care (2002) as Linda Peeno |
 | Goose (2002) as Narrator (voice) |
 | Mysteries of Love (2002) as Self |
 | I Am Sam (2001) as Randy Carpenter |
 | Novocaine (2001) as Jean Noble |
 | Daddy and Them (2001) as Ruby Montgomery |
 | Focus (2001) as Gertrude 'Gert' Hart |
 | Within These Walls (2001) as Sister Pauline Quinn |
 | Jurassic Park III (2001) as Ellie |
 | In the Small, Small Pond (2001) |
 | Dr. T & the Women (2000) as Peggy Travis |
 | A Season for Miracles (1999) as Berry Thompson |
 | October Sky (1999) as Miss Riley |
 | The Baby Dance (1998) as Wanda LeFauve |
 | Bastard Out of Carolina (1996) as Narrator (voice) |
 | Citizen Ruth (1996) as Ruth Stoops |
 | The Siege at Ruby Ridge (1996) as Vicki Weaver |
 | Down Came a Blackbird (1995) as Helen McNulty |
 | The Making of 'Jurassic Park' (1995) as Self / Ellie Sattler |
 | A Perfect World (1993) as Sally Gerber |
 | Rabbit Ears - The Song of Sacajawea (1993) as Narrator (voice) |
 | Jurassic Park (1993) as Ellie |
 | Afterburn (1992) as Janet Harduvel |
 | Rambling Rose (1991) as Rose |
 | Jonathan Ross Presents for One Week Only: David Lynch (1990) as Self |
 | Industrial Symphony No. 1: The Dream of the Brokenhearted (1990) as Heartbroken Woman |
 | Wild at Heart (1990) as Lula |
 | The Strange Case of Dr. Jekyll and Mr. Hyde (1989) as Rebecca Laymon |
 | Fat Man and Little Boy (1989) as Kathleen Robinson |
| | Production Story: Fat Man and Little Boy (1989) as Self |
 | Haunted Summer (1988) as Claire Clairmont |
 | No Frank in Lumberton (1988) as Self |
 | Blue Velvet (1986) as Sandy Williams |
 | Smooth Talk (1985) as Connie Wyatt |
 | Mask (1985) as Diana |
 | The Three Wishes of Billy Grier (1984) as Crissy |
 | Teachers (1984) as Diane |
 | Happy Endings (1983) as Audrey Constantine |
 | Ladies and Gentlemen, the Fabulous Stains (1982) as Jessica McNeil |
 | Foxes (1980) as Debbie |
 | Alice Doesn't Live Here Anymore (1974) as Girl Eating Ice Cream Cone (uncredited) |
 | White Lightning (1973) as Sharon Anne (uncredited) |
 | Peaked |
 | Behind the Lines as Self |
 | Morning as Cathy |
| | Monsanto as Dr Melinda Rogers |
 | The Way I See It Producer |
 | If Anything Happens I Love You Executive Producer |
 | Call Me Crazy: A Five Film Director |
| | Inland Empire Co-Producer |
| | Damaged Care Co-Producer |
| | Down Came a Blackbird Executive Producer |
| | The Gift Director |
| | Morning Executive Producer |
