 | Street Smart (2026) as Dr. Partovi |
 | The Dreadful (2026) as Morwen |
 | This Ordinary Thing (2025) as Self (voice) |
 | Renner (2025) as Salenus (voice) |
 | Knox Goes Away (2024) as Ruby Knox |
 | Daughter of the Bride (2023) as Diane |
 | Tell It Like a Woman (2022) as Dr. Partovi |
 | Confess, Fletch (2022) as Countess Sylvia de Grassi |
 | Gigi & Nate (2022) as Claire Gibson |
 | Moxie (2021) as Principal Shelly |
 | Pink Skies Ahead (2020) as Pamela |
 | Together in Pride: You Are Not Alone (2020) as Self |
 | Point Blank (2019) as Lieutenant Lewis |
 | The Cold Open (2019) |
 | Love You to Death (2019) as Camile Stoller |
 | In the Night I Remember Your Name (2018) as Pastor Joyce Speegle (voice) |
 | Fifty Shades Freed (2018) as Grace Grey |
 | Fifty Shades Darker (2017) as Grace Trevelyan Grey |
 | Get a Job (2016) as Katherine Dunn |
 | After Words (2015) as Jane Taylor |
 | Unity (2015) as Narrator (voice) |
 | Larry Gaye: Renegade Male Flight Attendant (2015) as President of the FAFAFA |
 | Grandma (2015) as Judy |
 | Fifty Shades of Grey (2015) as Dr. Grey |
 | You're Not You (2014) as Elizabeth |
 | Magic in the Moonlight (2014) as Mrs. Baker |
 | Elsa & Fred (2014) as Lydia |
 | Parkland (2013) as Doris Nelson |
 | The Wine of Summer (2013) as Shelley |
 | Eastwood Directs: The Untold Story (2013) as Self |
 | If I Were You (2013) as Madelyn |
 | Someday This Pain Will Be Useful to You (2012) as Marjorie Dunfour |
 | Innocent (2011) as Barbara Sabich |
 | Detachment (2011) as Principal Carol Dearden |
 | Amanda Knox: Murder on Trial in Italy (2011) as Edda Mellas |
 | Sex and Lies in Sin City (2009) as Becky Binion |
 | The Maiden Heist (2009) as Rose Barlow |
 | Home (2009) as Inga |
 | The Courageous Heart of Irena Sendler (2009) as Janina Krzyżanowska |
 | Whip It (2009) as Brooke Cavendar |
 | Christmas Cottage (2008) as Maryanne Kinkade |
 | When Darkness Came: The Making of 'The Mist' (2008) as Self |
 | The Tower (2008) as Zoe Cafritz |
 | The Mist (2007) as Mrs. Carmody |
 | Fog City Mavericks (2007) as Self |
 | Into the Wild (2007) as Billie McCandless |
 | Rails & Ties (2007) as Megan Stark |
 | The Invisible (2007) as Diane Powell |
 | Canvas (2006) as Mary Marino |
 | The Dead Girl (2006) as Melora |
 | The Hoax (2006) as Edith Irving |
 | In from the Night (2006) as Vicki Miller |
 | American Dreamz (2006) as First Lady |
 | Wrestling with Angels: Playwright Tony Kushner (2006) as Self |
| | Sweet Tornado: Margo Jones and the American Theater (2006) as Narrator |
 | Felicity: An American Girl Adventure (2005) as Mrs. Martha Merriman |
 | American Gun (2005) as Janet Huttenson |
 | Willa Cather: The Road Is All (2005) as Voice of Willa Cather |
 | Shelter from the Storm: A Concert for the Gulf Coast (2005) as Self - Presenter |
 | Bad News Bears (2005) as Liz Whitewood |
 | P.S. (2004) as Missy Goldberg |
 | See You in My Dreams (2004) as Angela Brown |
| | Mystic River: Beneath the Surface (2004) as Self |
 | Welcome to Mooseport (2004) as Grace Sutherland |
 | She's Too Young (2004) as Trish Vogul |
 | Mona Lisa Smile (2003) as Nancy Abbey |
| | Mystic River: From Page to Screen (2003) as Self |
 | Mystic River (2003) as Celeste Boyle |
 | Casa de los Babys (2003) as Nan |
 | King of Texas (2002) as Mrs. Susannah Lear Tumlinson |
 | Guilty Hearts (2002) as Jenny Moran |
 | Walking Shadow (2001) as Susan Silverman |
 | Gaudi Afternoon (2001) as Frankie |
 | Thin Air (2000) as Susan Silverman |
 | Pollock (2000) as Lee Krasner |
 | Space Cowboys (2000) as Sara Holland |
| | From Where I Sit (2000) as Sharon |
 | Small Vices (1999) as Susan Silverman |
 | Curtain Call (1998) as Michelle Tippet |
 | Meet Joe Black (1998) as Allison |
 | Labor of Love (1998) as Annie Pines |
 | Desperate Measures (1998) as Dr. Samantha Hawkins |
 | Flubber (1997) as Dr. Sara Jean Reynolds |
 | Path to Paradise: The Untold Story of the World Trade Center Bombing (1997) as Nancy Floyd |
 | The Daytrippers (1997) as Libby |
 | Far Harbor (1996) as Arabella |
 | The First Wives Club (1996) as Dr. Leslie Rosen |
 | The Spitfire Grill (1996) as Shelby Goddard |
 | Spy Hard (1996) as Miss Cheevus |
 | Convict Cowboy (1995) as Maggie Sinclair |
 | Talking With (1995) as Laurie (segment "Clear Glass Marbles") |
 | Fever (1994) as Lacy |
 | Safe Passage (1994) as Cynthia |
 | In the Wings: Angels in America On Broadway (1993) |
| | Geoffrey Beene 30 (1993) |
 | Used People (1992) as Norma |
 | Crush (1992) as Lane |
 | Late for Dinner (1991) as Joy Husband |
 | In Broad Daylight (1991) as Adina Rowan |
 | Miller's Crossing (1990) as Verna |
 | Kojak: None So Blind (1990) as Angelina |
 | Superman's 50th Anniversary: A Celebration of the Man of Steel (1988) as Marcia Connelly |
 | Not Only Strangers (1979) as Jennie |
| | In the Echo as Marcia |
