 | The Debut (2026) as Jerry |
 | Downton Abbey: The Grand Finale (2025) as Harold Levinson |
 | Downton Abbey Celebrates the Grand Finale (2025) as Self |
 | Old Time Radio: The Specter of Christmas (2025) as Narrator |
 | The Holdovers (2023) as Paul Hunham |
 | Woodpeckers: The Hole Story (2022) as Self - Narrator |
 | A Mouthful of Air (2021) as Dr. Sylvester |
 | Season of the Osprey (2021) as Narrator |
 | Jungle Cruise (2021) as Nilo Nemolato |
 | Gunpowder Milkshake (2021) as Nathan |
 | Wax Paul Now (2019) as Self |
 | Private Life (2018) as Richard Grimes |
 | I Think We're Alone Now (2018) as Patrick |
 | The Catcher Was a Spy (2018) as Sam Goudsmit |
 | Sex, Lies and Butterflies (2018) as Narrator (voice) |
 | Jim & Andy: The Great Beyond (2017) as Self |
 | Morgan (2016) as Dr. Alan Shapiro |
 | The Phenom (2016) as Dr. Mobley |
 | Ratchet & Clank (2016) as Chairman Drek (voice) |
 | Straight Outta Compton (2015) as Jerry Heller |
 | The Little Prince (2015) as The Academy Teacher (voice) |
 | Madame Bovary (2015) as Monsieur Homais |
 | Love & Mercy (2015) as Dr. Eugene Landy |
 | San Andreas (2015) as Dr. Lawrence Hayes |
 | Goldfish (2015) as Goldfish (voice) |
 | Giant Sloth (2015) as Gordon Boonewell |
 | The Wages of Heroism: Making The Amazing Spider-Man 2 (2014) as Self |
 | The Amazing Spider-Man 2 (2014) as Aleksei Sytsevich |
 | River of Fundament (2014) as Ptah-Nem-Hotep |
| | Hoke (2014) as Hoke Mosely |
 | Wolfpack Only: The Hangover Retrospective (2013) as Self |
 | Saving Mr. Banks (2013) as Ralph |
 | 12 Years a Slave (2013) as Theophilus Freeman |
 | Parkland (2013) as Abraham Zapruder |
 | Romeo & Juliet (2013) as Friar Laurence |
 | All Is Bright (2013) as Dennis Girard |
 | Turbo (2013) as Chet (voice) |
 | The Congress (2013) as Dr. Barker |
 | Love, Marilyn (2013) as Self |
 | John Dies at the End (2013) as Arnie Blondestone |
 | PBS Nature - An Original DUCKumentary (2012) as Narrator |
| | Citizens of Cosmopolis (2012) as Self |
 | Rock of Ages (2012) as Paul Gill |
 | Cosmopolis (2012) as Benno Levin |
 | Too Big to Fail (2011) as Ben Bernanke |
 | The Ides of March (2011) as Tom Duffy |
 | The Hangover Part II (2011) as Kingsley |
 | Win Win (2011) as Mike Flaherty |
 | Ironclad (2011) as King John |
 | Barney's Version (2010) as Barney Panofsky |
 | The Haunted World of El Superbeasto (2009) as Dr. Satan (voice) |
 | The Last Station (2009) as Vladimir Chertkov |
 | Cold Souls (2009) as Paul |
 | Saturday Night Live: The Best of Amy Poehler (2009) as Uncle Chaz (archive footage) |
 | Duplicity (2009) as Richard Garsik |
 | Pretty Bird (2008) as Rick Honeycutt |
 | Fred Claus (2007) as Nick (Santa) Claus |
| | Příliš hlučna samota (2007) as Hanta (voice) |
 | Trumbo (2007) as Self |
 | The Nanny Diaries (2007) as Mr. X |
 | Shoot 'Em Up (2007) as Hertz |
 | The Hawk Is Dying (2007) as Georges Gattling |
 | The Amazing Screw-On Head (2006) as Screw-On Head (voice) |
 | The Illusionist (2006) as Inspector Uhl |
 | The Ant Bully (2006) as Stan Beals (voice) |
 | Lady in the Water (2006) as Cleveland Heep |
 | Cinderella Man (2005) as Joe Gould |
 | The Fan and the Flower (2005) as Narrator (voice) |
 | Robots (2005) as Tim the Gate Guard (voice) |
 | Sideways (2004) as Miles |
 | Paycheck (2003) as Shorty |
 | American Splendor (2003) as Harvey Pekar |
 | The True Story of the 3 Little Pigs! (2003) as Narrator |
 | Confidence (2003) as Gordo |
 | The Pentagon Papers (2003) as Anthony Russo |
 | Thunderpants (2002) as Johnson J. Johnson |
 | Big Fat Liar (2002) as Marty Wolf |
 | Storytelling (2001) as Toby Oxman |
 | Planet of the Apes (2001) as Limbo |
 | Duets (2000) as Todd Woods |
 | Big Momma's House (2000) as John |
 | 1961 (2000) as Ted Hedley |
 | If These Walls Could Talk 2 (2000) as Ted Hedley |
 | Man on the Moon (1999) as Bob Zmuda |
 | Cradle Will Rock (1999) as Carlo |
 | Winchell (1998) as Herman Klurfeld |
 | Safe Men (1998) as Veal Chop |
 | The Negotiator (1998) as Rudy |
 | Saving Private Ryan (1998) as Sergeant Hill |
 | Doctor Dolittle (1998) as Blaine (uncredited) |
 | The Truman Show (1998) as Simeon |
 | Tourist Trap (1998) as Jeremiah Piper |
 | Deconstructing Harry (1997) as Professor Abbott |
 | My Best Friend's Wedding (1997) as Bellman |
 | Private Parts (1997) as Kenny |
 | Donnie Brasco (1997) as FBI Technician |
 | Arresting Gena (1997) as Detective Wilson |
 | A Further Gesture (1997) as Hotel Clerk |
 | Breathing Room (1996) as George |
 | Before and After (1996) as Courtroom Audience (uncredited) |
 | Sabrina (1995) as Scott |
 | Mighty Aphrodite (1995) as Extras Guild Researcher |
 | Singles (1992) as Kissing Man |
 | Past Midnight (1992) as Larry Canipe |
 | She'll Take Romance (1990) as Heckler #2 |
| | Untitled DJ Art Bell Biopic as DJ Art Bell |
| | Boutique as Calvin |
| | The Statement |
| | A Sprinkle of History as Sam Born |
| | Wax Paul Now Thanks |
| | John Dies at the End Executive Producer |
| | Boutique Producer |
