 | Campeón Gabacho (2026) |
 | Radiator Springs Racers | Disneyland Resort (2025) as Ramone (voice) |
 | Cheech & Chong's Last Movie (2025) as Self |
 | Alexander and the Terrible, Horrible, No Good, Very Bad Road Trip (2025) as Gil Morales |
 | The Long Game (2024) as Pollo |
 | Champions (2023) as Julio |
 | Shotgun Wedding (2022) as Robert Rivera |
 | Angry Neighbors (2022) as Hector (voice) |
 | Cypress Hill: Insane in the Brain (2022) as Self |
 | Nash Bridges (2021) as Joe Dominguez |
 | A Song for Cesar: Beware a Movement That Sings (2021) as Self |
 | Classic Albums: Frank Zappa & The Mothers Of Invention - Freak Out! (2021) as Self |
| | Quentin Tarantino: From a Movie Buff to a Hollywood Legend (2021) as Self (archive footage) |
 | The War with Grandpa (2020) as Danny |
 | AGFA Mystery Mixtape #4: Follow Your Own Star (2020) as Self |
 | The AGFA Mystery Mixtape Vault (2020) as (archive footage) |
 | Inmate #1: The Rise of Danny Trejo (2019) as Self |
 | Carlos Almaraz: Playing with Fire (2019) as Self |
 | Coco (2017) as Corrections Officer (voice) |
 | Elena of Avalor: Realm of the Jaquins (2017) as Quita Moz (voice) |
 | Cars 3 (2017) as Ramone (voice) |
 | Good Fortune (2016) as Self |
 | Dark Harvest (2016) as Ricardo |
 | El Americano: The Movie (2016) as Martin (voice) |
 | The Latin Explosion: A New America (2015) as Self |
 | The Book of Life (2014) as Pancho Rodriguez (voice) |
 | The Radiator Springs 500½ (2014) as Ramone (voice) |
 | Cheech & Chong's Animated Movie! (2013) as (voices) |
 | Spinning (2013) as Ramone (voice) |
 | El Santos vs la Tetona Mendoza (2012) as Narrador / El Charro (voice) |
 | George Lopez: It's Not Me, It's You (2012) as Self |
 | Cars 2 (2011) as Ramone (voice) |
 | Hoodwinked Too! Hood VS. Evil (2011) as Mad Hog (voice) |
 | Pure Country 2: The Gift (2010) as Angel Pedro |
 | Machete (2010) as Padre Cortez |
 | Cheech & Chong's Hey Watch This (2010) as Self |
 | The Perfect Game (2009) as Padre Estaban |
 | Waking Sleeping Beauty (2009) as Tito (voice) (archive footage) |
 | Race to Witch Mountain (2009) as Eddie |
 | Expecting a Miracle (2009) as Father Arturo |
 | Cheech & Chong Roasted (2008) as Self |
 | Beverly Hills Chihuahua (2008) as Manuel (voice) |
| | Bloodsucking Cinema (2007) as Self |
 | Uncle P (2007) as Juan |
 | Grindhouse (2007) as Padre (segment "Planet Terror") |
 | Planet Terror (2007) as Priest |
 | Geared-Up (2006) |
 | Mater and the Ghostlight (2006) as Ramone (voice) |
 | AKA Tommy Chong (2006) as Himself |
 | Cars (2006) as Ramone (voice) |
 | Cheech Marin & Friends: Live from South Beach (2006) as Self - Host |
 | Dizzy & Bop's Big Adventure: The Great Music Caper (2006) as Dr. Hammer (voice) |
 | Underclassman (2005) as Captain Victor Delgado |
 | Christmas with the Kranks (2004) as Officer Salino |
 | The Lion King 1½ (2004) as Banzai (voice) |
 | See You in My Dreams (2004) as Esteban |
| | Timon & Pumbaa's Virtual Safari 1.5 (2004) as Banzai (voice) (archive sound) |
 | Good Boy! (2003) as The Greater Dane's Henchman (voice) |
 | Once Upon a Time in Mexico (2003) as Belini |
 | Tracey Ullman in the Trailer Tales (2003) as Himself |
 | Chavez Ravine: A Los Angeles Story (2003) as Narrator |
 | Masked and Anonymous (2003) as Prospero |
 | Spy Kids 3-D: Game Over (2003) as Felix Gumm |
 | The Brothers Garcia: Mysteries of the Maya (2003) as Don Cortez |
 | This So-Called Disaster (2003) as Esteban |
 | Spy Kids 2: The Island of Lost Dreams (2002) as Felix Gumm |
 | The Original Latin Kings of Comedy (2002) as Himself |
 | Laughing Out Loud: America's Funniest Comedians (2001) as Self (archive footage) |
 | Spy Kids (2001) as Felix Gumm |
 | Picking Up the Pieces (2000) as Mayor Machado |
 | Luminarias (2000) |
 | The Nuttiest Nutcracker (1999) as Mac (Voice) |
 | Grass (1999) as Self (archive footage) |
 | The Venice Project (1999) as Cheech Marin |
 | Chato's Kitchen (1999) |
 | Breakfast with Einstein (1998) as Einstein (voice) |
 | Paulie (1998) as Ignacio |
 | Tin Cup (1996) as Romeo Posar |
 | The Great White Hype (1996) as Julio Escobar |
 | From Dusk Till Dawn (1996) as Border Guard / Chet Pussy / Carlos |
 | Charlie's Ghost Story (1995) as Coronado |
 | The Courtyard (1995) as Angel Steiner |
 | Desperado (1995) as Short Bartender |
 | 'Twas the Night Before Bumpy (1995) as Juaquin Gusanito Sin Manos (voice) |
 | The Magic of the Golden Bear: Goldy III (1994) as Master Borgia |
 | The Lion King (1994) as Banzai (voice) |
 | A Million to Juan (1994) as Shell Shock |
 | The Cisco Kid (1994) as Pancho |
 | Sesame Street Jam: A Musical Celebration (1993) as Self (segment "New Way to Walk") |
 | Walt Disney World Very Merry Christmas Parade (1992) as Self |
 | FernGully: The Last Rainforest (1992) as Stump (voice) |
| | La Pastorela: The Shepherd's Tale (1991) as El Cosmico |
 | The Shrimp on the Barbie (1990) as Carlos |
 | Mother Goose Rock 'n' Rhyme (1990) as Carnival Barker |
 | Far Out Man (1990) as Himself |
 | Help Save Planet Earth (1990) as Self |
 | Rude Awakening (1989) as Jesús Monteya |
 | Ghostbusters II (1989) as Dock Supervisor |
 | Troop Beverly Hills (1989) as Cheech Marin |
 | Oliver & Company (1988) as Tito (voice) |
 | Mickey's 60th Birthday (1988) as Disneyland Janitor |
 | Fatal Beauty (1987) as Bartender |
 | Born in East L.A. (1987) as Rudy |
 | Charlie Barnett's Terms of Enrollment (1986) as Elvis Friend & Fan |
 | Echo Park (1985) as Syd |
 | Get Out of My Room (1985) as Cheech |
 | After Hours (1985) as Neil |
 | Cheech & Chong's The Corsican Brothers (1984) as Corsican Brother |
 | Cannonball Run II (1984) as Tire Store Employee (uncredited) |
 | Return Engagement (1983) as Self |
 | Yellowbeard (1983) as El Segundo |
 | Group Madness (1983) as Self |
 | Still Smokin (1983) as Cheech |
 | It Came from Hollywood (1982) as Self |
 | Things Are Tough All Over (1982) as Cheech / Mr. Slyman |
 | Nice Dreams (1981) as Cheech |
 | Cheech & Chong's Next Movie (1980) as Cheech / Dwayne "Red" Mendoza |
 | Up in Smoke (1978) as Pedro |
| | Cheech and Chong Perform (1978) as Himself |
 | Cheech and Chong Perform Again?! (1978) as Himself |
 | Basketball Jones (1974) |
 | Coyote as Javier |
 | Naya: Legend of the Golden Dolphin as Dude (voice) |
 | La Venganza Rodríguez as Don Madrazo (voice) |
| | Cheech & Chong's Animated Movie! Writer |
| | The Original Latin Kings of Comedy Writer |
| | Born in East L.A. Writer |
| | Born in East L.A. Director |
| | Get Out of My Room Writer |
| | Get Out of My Room Director |
| | Cheech & Chong's The Corsican Brothers Writer |
| | Still Smokin Writer |
| | Things Are Tough All Over Writer |
| | Nice Dreams Writer |
| | Cheech & Chong's Next Movie Writer |
| | Up in Smoke Writer |
