Trailer
 | Pauly Shore as Bud Macintosh |
 | Stephen Baldwin as Doyle Johnson |
 | William Atherton as Dr. Noah Faulkner |
 | Joey Lauren Adams as Monique |
 | Teresa Hill as Jen |
 | Henry Gibson as William Leaky |
 | Kevin West as T.C. Romulus |
 | Denise Dowse as Olivia Biggs |
 | Dara Tomanovich as Mimi Simkins |
 | Rose McGowan as Denise |
 | Taylor Negron as Russell |
 | Patricia Hearst as Doyle's Mother |
 | Jeremy Jordan as Trent |
 | Trevor St. John as Parker |
 | Channon Roe as Roach |
 | Kylie Minogue as Dr. Petra von Kant |
 | Kyle Gass as Tenacious D |
 | Jack Black as Tenacious D |
 | Christopher Dye as Partier |
 | Loomis Fall as Drummer |
| Robbie Thibaut Jr. as Young Doyle |
 | Adam Weisman as Young Bud |
 | Brian Hayes Currie as Guard |
| Butch McCain as Reporter Joachim West |
 | Roger Clinton Jr. as Prof. Bloom |
| Mark Burton as Guy |
| Joe Sib as Singer |
| Soda Pop as Guitarist |
 | Rene L. Moreno as Partier |
| Molly Bryant as Bio-Dome Technician |
 | Ben McCain as Anchor Aries West |
| Katherine Kousi as Vigilante |
 | Elizabeth Guber as Vigilante |
 | Tucker Smallwood as Cmdr. Gates, SWAT Team |
 | Phil LaMarr as Assistant |
 | Paul Eiding as Assistant |
 | Rodger Bumpass as Narrator |
 | Phil Proctor as Axl |
| Cecile Krevoy as Woman in Bandstand |
| Production | |
| Steven Stabler | Producer |
Camera | |
| Phedon Papamichael | Director of Photography |
Production | |
| Bradley Jenkel | Producer |
Editing | |
| Christopher Greenbury | Editor |
Production | |
| Brad Krevoy | Producer |
Directing | |
| Jason Bloom | Director |
Writing | |
| Jason Blumenthal | Story |
| Scott Marcano | Writer |
| Adam Leff | Story |
| Mitchell Peck | Story |
| Kip Koenig | Writer |
Directing | |
| Rod Smith | First Assistant Director |
Crew | |
| Anita Hart | Stunts |
| Kurt Bryant | Stunt Coordinator |
| Joni Avery | Stunts |
Sound | |
| Andrew Gross | Original Music Composer |
Crew | |
| Michael J. Sarna | Stunts |
| Denney Pierce | Utility Stunts |
| Thomas DeWier | Utility Stunts |
Art | |
| Amy Ancona | Set Decoration |
Crew | |
| James Ryan | Stunts |
| Brett A. Jones | Stunts |
| Nick Brett | Utility Stunts |
Production | |
| Michael Rotenberg | Executive Producer |
Crew | |
| Hugh Aodh O'Brien | Stunts |
Camera | |
| Christopher Faloona | Additional Photography |
Art | |
| P. Michael Johnston | Production Design |
Crew | |
| Perry Barndt | Stunts |
Production | |
| Mitchell Peck | Executive Producer |
| Adam Leff | Executive Producer |
| Elaine Dysinger | Co-Producer |
Crew | |
| Lou Carlucci | Special Effects |
Camera | |
| Patrick Loungway | Second Unit Director of Photography |
Production | |
| Jason Blumenthal | Executive Producer |
| Dan Etheridge | Co-Producer |
| Dan Parada | Casting |
Costume & Make-Up | |
| Dugg Kirkpatrick | Key Hair Stylist |
| Mary Claire Hannan | Costume Design |
