Trailer
 | Benedict Cumberbatch as Stephen Hawking |
 | Peter Firth as Sir Fred Hoyle |
 | Tom Ward as Roger Penrose |
 | Lisa Dillon as Jane Wilde |
 | John Sessions as Dennis Sciama |
 | Phoebe Nicholls as Isobel Hawking |
 | Michael Brandon as Arno Penzias |
 | Tom Hodgkins as Robert Wilson |
 | Alice Eve as Martha Guthrie |
 | Adam Godley as Frank Hawking |
 | Matthew Marsh as Dr. John Holloway |
 | Anastasia Hille as Nurse Susan McClean |
 | Christian Rubeck as Reporter |
 | Bertie Carvel as George Ellis |
 | Carolina Giammetta as Lidia Sciama |
 | Sebastian Armesto as Robert Silkin |
| Rohan Siva as Jayant Narlikar |
| Deirdre Costello as Barmaid |
 | Linda Spurrier as Train Passenger |
 | Anthony Howell as Hamlet |
| Che Cartwright as Guildenstern |
 | Leon Ockenden as Rosencrantz |
 | James Warrior as Cab Driver |
 | David McKail as Frink |
 | Rory Copus as Edgar |
 | Philip McGinley as Chris |
 | Charlie Beall as Hugh |
| Mark Wells as Cyclist |
| Directing | |
| Philip Martin | Director |
Production | |
| Jessica Pope | Producer |
| Laura Mackie | Executive Producer |
| John Lynch | Executive Producer |
| Grace Hartley | Associate Producer |
| Simon Bird | Associate Producer |
Sound | |
| Murray Gold | Original Music Composer |
Camera | |
| Julian Court | Director of Photography |
Editing | |
| Trevor Waite | Editor |
Production | |
| Janey Fothergill | Casting |
Art | |
| Donal Woods | Production Design |
| Cissy Cook | Art Direction |
Costume & Make-Up | |
| Joanna Eatwell | Costume Design |
| Alison Elliott | Makeup Designer |
| Faye De Bremaeker | Makeup Supervisor |
Sound | |
| Colin Cooper | Foley Mixer |
| Lee Crichlow | Sound Effects Editor |
| Rory Farnan | Dialogue Editor |
| Lee Walpole | Dialogue Editor |
Writing | |
| Peter Moffat | Writer |
